| 中文名 | 克拉红霉素 |
| 英文名 | Clarithromycin |
| 别名 | 克拉仙 克拉霉素 克红霉素 克拉红霉素 克拉仙霉素 克拉霉素(标准品) 克拉霉素-13C-D3 克拉霉素 CLARITHROMYCIN CLARITHROMYCIN 克拉霉素 |
| 英文别名 | TE-03 A-56268 Klacid Biaxin A-56268 Abbott56268 Clarithromycin chlarithromycin 6-O-Methylerythromycin Erythromycin,6-O-methyl- CLARITHROMYCIN(SUBJECTTOPATENTFREE) 6-O-Methylerythromycin, A-56268, TE-031, Biaxin 6-(4-DIMETHYLAMINO-3-HYDROXY-6-METHYLTETRAHYDROPYRAN-2-YL-OXY)-14-ETHYL-12,13-DIHYDROXY-4-(5-HYDROXY) (3R,4S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione(non-preferred name) (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione(non-preferred name) |
| CAS | 81103-11-9 |
| EINECS | 1806241-263-5 |
| 化学式 | C38H69NO13 |
| 分子量 | 747.95 |
| InChI | InChI=1/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22?,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1 |
| InChIKey | AGOYDEPGAOXOCK-KCBOHYOISA-N |
| 密度 | 1.1334 (rough estimate) |
| 熔点 | 217-220°C |
| 沸点 | 86℃ |
| 比旋光度 | D24 -90.4° (c = 1 in CHCl3) |
| 闪点 | >110°(230°F) |
| 水溶性 | 99.48mg/L(20 ºC) |
| 蒸汽压 | 5.06E-30mmHg at 25°C |
| 溶解度 | Soluble in DMSO |
| 折射率 | -92 ° (C=1, CHCl3) |
| 酸度系数 | pKa 8.99(H2O t=25.0 I=0.167) (Uncertain) |
| 存储条件 | -20°C |
| 稳定性 | Store in Freezer |
| 外观 | powder |
| 颜色 | colorless to faint yellow |
| Merck | 14,2339 |
| 物化性质 | 白色结晶性粉末或无色针状结晶，无臭，味苦。较易溶于氯仿或丙酮，微溶于乙醇，yimi或甲醇，几不溶于水。从氯仿一异丙醚(1：2)得无色针状结晶，熔点217～220℃(分解)；或从乙醇结晶，熔点222～225℃。[α]{D24-90.4°(C=1，氯仿)。UVZui大吸收(氯仿)：288nm(ε27.9)。急性毒性LD50雄、雌小鼠，雄、雌大鼠(mg/kg)：2740，2700，3470，2700口服；1030．850，669，753腹腔注射。 |
| MDL号 | MFCD00865140 |
